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Abcam INCA-6, calcineurin-NFAT interaction inhibitor, 50MG

Catalog No. 502705064
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MW 284.31 g/mol, Purity >97%. Potent, cell-permeable, selective calcineurin-NFAT interaction inhibitor (Kd = 800 nM). Blocks NFAT dephosphorylation, cytokine mRNA induction and nuclear import (~40 μM). Unlike CsA (ab120114) and FK506 (ab120223) INCA-6 does not indiscriminately block other calcineurin substrates. Anti-inflammatory agent. Active in vitro and in vivo.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-5064 Supplier Abcam Supplier No. AB14586450MG
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MW 284.31 g/mol, Purity >97%. Potent, cell-permeable, selective calcineurin-NFAT interaction inhibitor (Kd = 800 nM). Blocks NFAT dephosphorylation, cytokine mRNA induction and nuclear import (~40 μM). Unlike CsA (ab120114) and FK506 (ab120223) INCA-6 does not indiscriminately block other calcineurin substrates. Anti-inflammatory agent. Active in vitro and in vivo.

The product is subject to the following: Abcam Restricted Use Statement

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