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Medchemexpress LLC INCB059872 dihydrochloride | 3062683-32-0 | 97.9% | C23H34N2O3 • 2HCl | 50 MG
Supplier: Medchemexpress LLC HY141677A50MG
INCB059872 dihydrochloride is a potent, selective, and irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1). It exhibits potential antineoplastic activity and can be used in acute myeloid leukemia (AML) research. It has been shown to decrease proliferation in THP-1 acute monocytic and MV4-11 acute myeloid leukemia cells, and to increase the levels of CD11B in THP-1 cells when used at a concentration of 100 nM.
- Potent, selective, and irreversible LSD1 inhibitor
- Potential antineoplastic activity
- Useful in acute myeloid leukemia (AML) research
- Decreases proliferation in acute monocytic and myeloid leukemia cells
- Increases levels of CD11B in THP-1 cells
- Cited in Nature Medicine
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