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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.8% | C28H32N2O7 | 1 ML
Supplier: Medchemexpress LLC HY14299A10MM/1ML
Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It functions by inhibiting NF-κB activity in a β-arrestin2-dependent manner. This chemical property contributes to preventing further lung damage and improving lung function in conditions like chronic obstructive pulmonary disorder (COPD). It also has potential applications in cardiovascular disease research.
- Acts as an ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity via a β-arrestin2-dependent mechanism.
- Suppresses MMP-9 mRNA expression and activity.
- Reduces cell migration and inhibits NF-κB nuclear translocation.
- Active in normalizing cardiac remodeling in heart failure models.
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