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Indigo Biosciences INDIGO Biosciences Activation Reporter Assay System, Human CHRM1, 96-well
Supplier: Indigo Biosciences IB44001
This Human Cholinergic Receptor, Muscarinic 1 (CHRM1) Activation Reporter Assay System is a cell-based assay for screening compounds. It quantifies changes in luciferase activity to measure drug-induced changes in CHRM1 activity, identifying activators of CHRM1 or the coupled Ca+2-calcineurin / NFAT signal transduction pathway.
- Utilizes proprietary human cells engineered to constitutively express the human cholinergic receptor, muscarinic 1 (CHRM1).
- Measures drug-induced changes in CHRM1 activity through luciferase reporter gene expression.
- Designed for screening compounds that activate CHRM1 or the Ca+2-calcineurin / NFAT signal transduction pathway.
- Provided in a convenient 96-well format for high-throughput screening.
- Kit includes reporter cells, media, acetylcholine, detection reagents, and a collagen-coated assay plate.
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