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Indigo Biosciences INDIGO Biosciences Activation Reporter Assay System, Human CHRM1, 96-well

Catalog No. NC3978897
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This Human Cholinergic Receptor, Muscarinic 1 (CHRM1) Activation Reporter Assay System is a cell-based assay for screening compounds. It quantifies changes in luciferase activity to measure drug-induced changes in CHRM1 activity, identifying activators of CHRM1 or the coupled Ca+2-calcineurin / NFAT signal transduction pathway.

  • Utilizes proprietary human cells engineered to constitutively express the human cholinergic receptor, muscarinic 1 (CHRM1).
  • Measures drug-induced changes in CHRM1 activity through luciferase reporter gene expression.
  • Designed for screening compounds that activate CHRM1 or the Ca+2-calcineurin / NFAT signal transduction pathway.
  • Provided in a convenient 96-well format for high-throughput screening.
  • Kit includes reporter cells, media, acetylcholine, detection reagents, and a collagen-coated assay plate.

Catalog No. NC3978897 Supplier Indigo Biosciences Supplier No. IB44001
May include imposed supplier surcharges.
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This Human Cholinergic Receptor, Muscarinic 1 (CHRM1) Activation Reporter Assay System is a cell-based assay for screening compounds. It quantifies changes in luciferase activity to measure drug-induced changes in CHRM1 activity, identifying activators of CHRM1 or the coupled Ca+2-calcineurin / NFAT signal transduction pathway.

  • Utilizes proprietary human cells engineered to constitutively express the human cholinergic receptor, muscarinic 1 (CHRM1).
  • Measures drug-induced changes in CHRM1 activity through luciferase reporter gene expression.
  • Designed for screening compounds that activate CHRM1 or the Ca+2-calcineurin / NFAT signal transduction pathway.
  • Provided in a convenient 96-well format for high-throughput screening.
  • Kit includes reporter cells, media, acetylcholine, detection reagents, and a collagen-coated assay plate.

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