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Cayman Chemical IndIMIII thIosemIcarbazon 10mg
SDP

Supplier:  Cayman Chemical 3560110 MG

Encompass_Preferred

An anticancer agent; cytotoxic to A549, MCF-7 breast, MCF-7/DDP cisplatin-resistant breast, and Hl 7702 liver cancer cells (IC50s = 2.41, 1.97, 2.11 µM, and 8.95 µM, respectively); decreases PI3K, Akt, mTOR, P-gp, and GSH levels in MCF-7/DDP cells; reduces tumor weight and volume in an MCF-7/DDP mouse xenograft model at 2.5 µmol/kg; liposomes containing it induce apoptosis and pro-death autophagy in MCF-7/DDP cells, as well as reduce tumor volume and weight in an MCF-7/DDP mouse xenograft model

Catalog No. 50-291-3667


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