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Enzo Life Sciences Indirubin (1mg). CAS: 479-41-4
SDP

Supplier:  Enzo Life Sciences ALX270361M001

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Inhibitor of CDK and GSK. Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3β (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity. Formula: C16H10N2O2. MW: 262.3. Purity: ≥97% (HPLC). Appearance: Purple powder. Solubility: Soluble in DMSO (10mg/ml) or methanol (0.3mg/ml); sparingly soluble in aqueous buffers (12.5µg/ml). Use/Stability: Stable for at least 2 years when stored at +4°C in the dark. Stock solutions should be stored in the dark and used within 1 month. Long Term Storage: +4°C. Handling: Protect from light. Keep cool and dry.

Catalog No. 50-200-8507


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