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Medchemexpress LLC Indirubin-3'-oxime | 667463-82-3 | >99.1% | 277.28 | 1 ML
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Supplier:  Medchemexpress LLC HY13925410MM/1ML

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Indirubin-3'-oxime (IDR3O), a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Indirubin-3'-oxime directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3), with IC50s of 0.8 μM, 1.4 μM, and 1.0 μM, respectively. Indirubin-3'-oxime can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes.

  • Potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β).
  • Directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3).
  • Can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes.

Catalog No. 50-003-49318


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