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Indirubin-3'-oxime, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
160807-49-8
C16H11N3O2
277.283
LDEWQRSYYHTQRA-UHFFFAOYSA-N
indirubin-3'-monoxime,indirubin-3'-oxime,indirubin-3-oxime,indirubin-3monoxime,indirubin-3'-monooxime,indirubin-3-monoxime,3-3-hydroxyamino-1h-indol-2-yl indol-2-one,indirubin-3′-monoxime,z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime,3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
5326739
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO
This item is not returnable. View return policy
160807-49-8
C16H11N3O2
277.283
LDEWQRSYYHTQRA-UHFFFAOYSA-N
indirubin-3'-monoxime,indirubin-3'-oxime,indirubin-3-oxime,indirubin-3monoxime,indirubin-3'-monooxime,indirubin-3-monoxime,3-3-hydroxyamino-1h-indol-2-yl indol-2-one,indirubin-3′-monoxime,z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime,3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
5326739
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO

GSK-3β inhibitor. Also inhibits other protein kinases

Inhibitor of GSK-3β (IC 50 = 190 nM) and cyclin dependent kinases (cdks; IC 50 values are 0.05, 0.18 and 0.25-0.5 βM for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3β-mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation.

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Quantity 10mg
Formula Weight 277.28
Percent Purity >99%
Chemical Name or Material Indirubin-3'-oxime

Recommended Storage : Store at Room Temperature