AdipoGen Indole-3-carbinol

Supplier:  AdipoGen AGCR13637M500

Chemical. CAS 700-06-1. Formula C9H9NO. MW 147.2. Natural breakdown product of glucosinolates found in cruciferous vegetables. Widely used multifunctional aryl hydrocarbon receptor AhR agonist. AhR is emerging as a transcription factor involved in the regulation of both innate and adaptive immune responses in various immune cell types, including lymphocytes and antigen-presenting cells APCs. Studies have associated overexpression of AHR with the activation of cancer processes such as proliferation, epithelial-to-mesenchymal transition EMT, DNA damage, inflammation, migration and angiogenesis. Used to increase the population of innate lymphoid cells 3 ILC3 in gut microbiota. Chemopreventive agent that has multiple anticarcinogenic and antitumor properties and suppresses the proliferation of selective cancer cells, including breast cancer, prostate cancer, endometrial cancer, colon cancer and leukemic cells. Protects against nephrotoxicity. Proapoptotic.

Catalog No. 50-256-2256