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Medchemexpress LLC Indomethacin-d4 Methyl Ester | 1217064-61-3 | 98.4% | C20H14D4ClNO4 | 1 MG
SDP

Catalog No. 5000353937
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Indomethacin-d4 Methyl Ester is a deuterium-labeled form of Indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of both COX-1 and COX-2 enzymes. It demonstrates inhibitory activity with IC50s of 18 nM for human COX-1 and 26 nM for COX-2 in CHO cells. This compound has also been observed to disrupt autophagic flux by interfering with the normal function of lysosomes.

  • Deuterium labeled derivative of indomethacin
  • Potent and nonselective COX-1 and COX-2 inhibitor
  • Blood-brain barrier permeable
  • Disrupts autophagic flux through lysosomal interference
  • Useful as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS

Catalog No. 50-003-53937 Supplier Medchemexpress LLC Supplier No. HY14397S11MG
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Indomethacin-d4 Methyl Ester is a deuterium-labeled form of Indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of both COX-1 and COX-2 enzymes. It demonstrates inhibitory activity with IC50s of 18 nM for human COX-1 and 26 nM for COX-2 in CHO cells. This compound has also been observed to disrupt autophagic flux by interfering with the normal function of lysosomes.

  • Deuterium labeled derivative of indomethacin
  • Potent and nonselective COX-1 and COX-2 inhibitor
  • Blood-brain barrier permeable
  • Disrupts autophagic flux through lysosomal interference
  • Useful as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS

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