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Medchemexpress LLC Ingenol 3,20-dibenzoate | 59086-90-7 | 100.0% | 556.65 | 25 MG
Supplier: Medchemexpress LLC 25MGHY137295
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. It induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction, leading to morphologically typical apoptosis through de novo synthesis of macromolecules.
- Induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu
- Induces morphologically typical apoptosis through de novo synthesis of macromolecules
- Increases IFN-γ production and degranulation by NK cells
- Enhances NK cells degranulation when stimulated by A549 cells and H1299 cells
- Promotes UT-7/EPO cell proliferation
- Lessens anemia induced by 5-fluorouracil in an in vivo mouse model
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