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Medchemexpress LLC Ingenol 3,20-dibenzoate | 59086-90-7 | 100.0% | 556.65 | 25 MG
SDP

Catalog No. 5000350552
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Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. It induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction, leading to morphologically typical apoptosis through de novo synthesis of macromolecules.

  • Induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu
  • Induces morphologically typical apoptosis through de novo synthesis of macromolecules
  • Increases IFN-γ production and degranulation by NK cells
  • Enhances NK cells degranulation when stimulated by A549 cells and H1299 cells
  • Promotes UT-7/EPO cell proliferation
  • Lessens anemia induced by 5-fluorouracil in an in vivo mouse model

Catalog No. 50-003-50552 Supplier Medchemexpress LLC Supplier No. 25MGHY137295
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Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. It induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction, leading to morphologically typical apoptosis through de novo synthesis of macromolecules.

  • Induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu
  • Induces morphologically typical apoptosis through de novo synthesis of macromolecules
  • Increases IFN-γ production and degranulation by NK cells
  • Enhances NK cells degranulation when stimulated by A549 cells and H1299 cells
  • Promotes UT-7/EPO cell proliferation
  • Lessens anemia induced by 5-fluorouracil in an in vivo mouse model

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