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STEMCELL Technologies XL413 (Hydrochloride), Size: 5 mg
SDP

Supplier:  STEMCELL Technologies 1000542

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XL413 selectively inhibits the cell division cycle 7 (CDC7) kinase (IC50 = 3.4 nM), which is involved in the initiation and maintenance of DNA replication (Koltun et al.). XL413 displays selectivity for CDC7 kinase over a panel of 100 kinases (Sasi et al.). This product is supplied as the hydrochloride salt of the molecule.CANCER RESEARCH· Induces apoptosis and inhibits the proliferation of human colon adenocarcinoma cells in vitro (Koltun et al.).· Attenuates tumor growth in mice (Koltun et al.).

Catalog No. 50-206-9350


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