MilliporeSigma™ INS-1 832/3 Rat Insulinoma Cell Line

Description

INS-1 832/3 rat insulinoma cell line is a useful model for insulin secretion regulation and pancreatic islet beta-cell function studies.

• Glucose-stimulated insulin secretion (GSIS) is potentiated by pancreatic beta cells and is critical to the physiological control of blood glucose levels
• Insulin secretion is impaired in type 2 diabetes, and insight into the mechanisms and regulation of insulin secretion is fundamental to understanding the roles of beta cells in metabolic disease
• The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality
• Cells are tested negative for infectious diseases by a Mouse/Rat  Comprehensive CLEAR panel by Charles River Animal Diagnostic Services
• Cells are verified to be of rat origin and negative for inter-species contamination from mouse, Chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services
• Cells are negative for mycoplasma contamination

Specifications

• Content And Storage: Store in liquid nitrogen
• Format: Vial
• Quantity: ≥ 1 x 10⁶ cells/vial