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Cayman Chemical InS3-54-A18 10mg
Supplier: Cayman Chemical 3967810 MG
A STAT3 inhibitor; selectively inhibits the binding of STAT3 to DNA over STAT1 at 25 µM; inhibits STAT3 activity in a reporter assay using MDA-MB-231 cells at 20 µM; induces apoptosis in, and reduces migration and invasion of, A549 and MDA-MB-231 cells at 5 or 10 µM; reduces tumor volume in an A549 mouse xenograft model at 200 mg/kg
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