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ABclonal Technology INSR/IGF1R Rabbit mAb
SDP

Catalog No. 5000007465
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This gene encodes a member of the receptor tyrosine kinase family of proteins The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor Binding of insulin or other ligands to this receptor activates the insulin signaling pathway which regulates glucose uptake and release as well as the synthesis and storage of carbohydrates lipids and protein Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome Donohue syndrome and Rabson-Mendenhall syndrome Alternative splicing results in multiple transcript variants

Catalog No. 50-000-07465 Supplier ABclonal Technology Supplier No. A21984100UL
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This gene encodes a member of the receptor tyrosine kinase family of proteins The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor Binding of insulin or other ligands to this receptor activates the insulin signaling pathway which regulates glucose uptake and release as well as the synthesis and storage of carbohydrates lipids and protein Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome Donohue syndrome and Rabson-Mendenhall syndrome Alternative splicing results in multiple transcript variants

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