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ACROBiosystems Recombinant Protein;Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein;HEK293;100UG;IT1,Integrin alpha 4 beta 1,ITGA4&ITGB1,ITGA4&B1

Supplier:  ACROBiosystems IT1H52W1100UG

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Recombinant Protein;Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein;100UG;Recombinant Human ITGA4 & ITGB1 Heterodimer Protein (IT1-H52W1) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) & Gln 21 - Asp 728 (ITGB1) (Accession # P13612-1 (ITGA4) & P05556-1 (ITGB1)).;Human ITGA4 & ITGB1 Heterodimer Protein, produced by co-expression of ITGA4 and ITGB1, has a calculated MW of 111.4 kDa (ITGA4) & 83.7 kDa (ITGB1). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The predicted N-terminus is Tyr 34 (ITGA4) & Gln 21 (ITGB1). The reducing (R) protein migrates as 60-70 kDa and 80-85 kDa (ITGA4) and 100-133 kDa and 135-150 kDa (ITGB1) respectively due to glycosylation.;Immobilized Natalizumab at 1 μg/mL (100 μL/well) can bind Human ITGA4 & ITGB1 (Cat. No. IT1-H52W1) with a linear range of 1-16 ng/mL (QC tested).

Catalog No. 50-165-7776


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