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ACROBiosystems Recombinant Protein;Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein;HEK293;100UG;IT7,Integrin alpha 4 beta 7,ITGA4&ITGB7

Supplier:  ACROBiosystems IT7H52W4100UG

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Recombinant Protein;Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein;100UG;Recombinant Human ITGA4 & ITGB7 Heterodimer Protein (IT7-H52W4) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) & Glu 20 - His 723 (ITGB7) (Accession # P13612-1 (ITGA4) & P26010-1 (ITGB7)).;Human ITGA4 & ITGB7 Heterodimer Protein, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 111.4 kDa (ITGA4) & 81.8 kDa (ITGB7). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB7 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 100-115 kDa and 135-150 kDa (ITGA4) and 60-70 kDa and 80-85 kDa (ITGB7) respectively due to glycosylation.;Immobilized Natalizumab at 1 μg/mL (100 μL/well) can bind Human ITGA4 & ITGB7 (Cat. No. IT7-H52W4) with a linear range of 4-63 ng/mL (QC tested).

Catalog No. 50-165-7766


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