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ACROBiosystems Human Integrin Alpha V Beta 3 Protein, His Tag, Low Endotoxin, 1 mg

Catalog No. 501658932
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The human integrin alpha-V/beta-3 (ITGAV and ITGB3) heterodimer protein is a receptor for various ligands including fibronectin, vitronectin, and von Willebrand factor, and recognizes the R-G-D sequence. This protein is expressed in human 293 cells (HEK293) and is verified via mass spectrometry and MALS. It plays a significant role in viral interaction, acting as a receptor for pathogens such as human cytomegalovirus and Hantaan virus, and is involved in angiogenesis during HIV-1 infection.

  • Greater than 95% purity as determined by SDS-PAGE
  • Endotoxin level less than 0.01 EU per μg by LAL or rFC method
  • Calculated MW of 112.9 kDa (ITGAV) and 81.8 kDa (ITGB3)
  • SEC-MALS purity more than 85% with molecular weight 207-253 kDa
  • Validated via ELISA and SPR binding assays
  • Supplied as a lyophilized powder

Catalog No. 50-165-8932 Supplier ACROBiosystems Supplier No. IT3H52E31MG
May include imposed supplier surcharges.
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The human integrin alpha-V/beta-3 (ITGAV and ITGB3) heterodimer protein is a receptor for various ligands including fibronectin, vitronectin, and von Willebrand factor, and recognizes the R-G-D sequence. This protein is expressed in human 293 cells (HEK293) and is verified via mass spectrometry and MALS. It plays a significant role in viral interaction, acting as a receptor for pathogens such as human cytomegalovirus and Hantaan virus, and is involved in angiogenesis during HIV-1 infection.

  • Greater than 95% purity as determined by SDS-PAGE
  • Endotoxin level less than 0.01 EU per μg by LAL or rFC method
  • Calculated MW of 112.9 kDa (ITGAV) and 81.8 kDa (ITGB3)
  • SEC-MALS purity more than 85% with molecular weight 207-253 kDa
  • Validated via ELISA and SPR binding assays
  • Supplied as a lyophilized powder

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