Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502269637

STEMCELL Technologies Human Recombinant IL-13, Size: 1000 µg
SDP

Catalog No. 502269637
Encompass

Use interleukin 13 (IL-13) to promote B cell proliferation, induce class switching to IgG4 and IgE, and recruit and activate IgE-producing B cells (Hershey. J Allergy Clin Immunol, 2003). IL-13 is a cytokine important in type 2 immune responses and is expressed by T helper type 2 (Th2) cells and group 2 innate lymphoid cells (ILC2s) (Pulendran & Artis. Science, 2012). It binds a receptor composed of IL-4Ra and IL-13Ra1 or IL-13Ra2 (Wynn. Annu Rev Immunol, 2003) and is expressed on a wide range of cells.. Signaling through the IL-13 receptor activates the JAK/STAT and IRS-1/IRS-2 pathways. In vivo, IL-13 has a role in resistance to extracellular helminth parasites, as well as in airway hyperresponsiveness, allergic inflammation, tissue remodeling, tumor cell growth, and fibrosis (Wynn. Nat Rev Immunol, 2015). Human recombinant IL-13 from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 5 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: Interleukin-13, NC30.

This item is not returnable. View return policy
Catalog No. 50-226-9637 Supplier STEMCELL Technologies Supplier No. 78029.3
May include imposed supplier surcharges.
Add to Cart
Add to Cart
Request a Quote

missing translation for 'validMainframeMsg'

Use interleukin 13 (IL-13) to promote B cell proliferation, induce class switching to IgG4 and IgE, and recruit and activate IgE-producing B cells (Hershey. J Allergy Clin Immunol, 2003). IL-13 is a cytokine important in type 2 immune responses and is expressed by T helper type 2 (Th2) cells and group 2 innate lymphoid cells (ILC2s) (Pulendran & Artis. Science, 2012). It binds a receptor composed of IL-4Ra and IL-13Ra1 or IL-13Ra2 (Wynn. Annu Rev Immunol, 2003) and is expressed on a wide range of cells.. Signaling through the IL-13 receptor activates the JAK/STAT and IRS-1/IRS-2 pathways. In vivo, IL-13 has a role in resistance to extracellular helminth parasites, as well as in airway hyperresponsiveness, allergic inflammation, tissue remodeling, tumor cell growth, and fibrosis (Wynn. Nat Rev Immunol, 2015). Human recombinant IL-13 from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 5 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: Interleukin-13, NC30.

This item is not returnable. View return policy
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.