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Cayman Chemical InterleukIn-13humnrecomb 5ug

Supplier: Cayman Chemical 404675 UG

A STING agonist induces expression of an IFN3-inducible SEAP reporter gene and an IFN-b-inducible reporter gene in cell-based assays (EC50s 52.9 and 116 nM respectively) increases the expression of mRNA encoding IFN-B and CXCL10 and phosphorylation of TBK1 IRF3 and STING in THP-1 monocytes at 4 6 and 8 UM reduces tumor volume without affecting body weight in a CT26 murine colon cancer model at 0.25 mg/kg every other day
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