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Sigma Aldrich Fine Chemicals Biosciences Intracellular Hydrogen Per
Supplier: Sigma Aldrich Fine Chemicals Biosciences MAK1641KT

Hydrogen peroxide a reactive oxygen species produced through the metabolism of molecular oxygen serves as both an intracellular signaling messenger and a source of oxidative stress. Hydrogen peroxide is generated in cells via multiple mechanisms such as the NOX-mediated ROS production by neutrophils and macrophages (respiratory burst) or by the dismutase of superoxide anions produced as a result of electron leak during mitochondrial respiration. Abnormal hydrogen peroxide production contributes to oxidative cell damage and the progression of diseases such as asthma atherosclerosis osteoporosis and neurodegeneration.
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