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Cayman Chemical InTRleukIn18 RabbIt Monclo
Supplier: Cayman Chemical 38092100 UL
ABarrestin-biased positive allosteric modulator of NTSR1 binds to NSTR1 and increases neurotensin-1 affinity for NSTR1 in HEK293 cells expressing the human receptor from 0.01-10 UM inducesBarrestin recruitment and NTSR1 internalization in cell-based assays from 0.03-30 UM attenuates cocaine- or methamphetamine-induced hyperlocomotion in wild-type but notBarrestin-2 knockout mice at 12 mg/kg reduces cocaine self-administration in mice
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