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Bio X Cell Monoclonal Antibody, anti-mouse PD-1, RMP1-14, 50 MG
Supplier: Bio X Cell BP0146R050MG
The RMP1-14 monoclonal antibody reacts with mouse PD-1 (CD279), a cell surface receptor crucial for peripheral tolerance and autoimmune disease prevention. It inhibits T-cell activation upon ligand binding and blocks PD-L1-Ig and PD-L2-Ig binding to PD-1.
- Clone: RMP1-14
- Reactivities: Mouse
- Isotype: Rat IgG2a, κ
- Conjugation: Unconjugated
- Formulation: PBS, pH 7.0
- Production: Purified from animal-free facility by Protein G
- Endotoxin: ≤0.5EU/mg
- Aggregation: <5%
- Purity: ≥95% (SDS-PAGE)
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage: 4°C; do not freeze
- Applications: In vivo PD-1/PD-L blocking, in vitro organoids
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