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Bio X Cell Anti-Human CD117, SR-1, Mouse IgG2a, 5 MG

Supplier:  Bio X Cell BE0380R005MG

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The SR-1 monoclonal antibody reacts with the extracellular domain of human c-Kit (CD117). This 145 kDa transmembrane tyrosine kinase is expressed on hematopoietic progenitor cells, mast cells, and acute myeloid leukemia (AML) cells. This antibody is reported to deplete c-Kit+ cells when administered in vivo.

  • Clone: SR-1
  • Reactivity: human
  • Isotype: mouse IgG2a, κ
  • Immunogen: human leukemic cell line OCIMl
  • Reported applications: in vivo c-Kit+ cell depletion, in vitro c-Kit targeting, immunohistochemistry (frozen)
  • Formulation: PBS, pH 7.0 (no stabilizers or preservatives)
  • Endotoxin: ≤1EU/mg
  • Purity: ≥95%
  • Sterility: 0.2 μm filtration
  • Purification: Protein A
  • Molecular weight: 150 kDa
  • Storage: store at 4°C, do not freeze

Catalog No. NC2468367


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