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Bio X Cell Anti-Human CD117, SR-1, Mouse IgG2a, 5 MG
Supplier: Bio X Cell BE0380R005MG
The SR-1 monoclonal antibody reacts with the extracellular domain of human c-Kit (CD117). This 145 kDa transmembrane tyrosine kinase is expressed on hematopoietic progenitor cells, mast cells, and acute myeloid leukemia (AML) cells. This antibody is reported to deplete c-Kit+ cells when administered in vivo.
- Clone: SR-1
- Reactivity: human
- Isotype: mouse IgG2a, κ
- Immunogen: human leukemic cell line OCIMl
- Reported applications: in vivo c-Kit+ cell depletion, in vitro c-Kit targeting, immunohistochemistry (frozen)
- Formulation: PBS, pH 7.0 (no stabilizers or preservatives)
- Endotoxin: ≤1EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Purification: Protein A
- Molecular weight: 150 kDa
- Storage: store at 4°C, do not freeze
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