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Bio X Cell Anti-CD47, Clone MIAP410, Mouse IgG1, 100 MG
Supplier: Bio X Cell BE0283R100MG
The MIAP410 monoclonal antibody reacts with mouse CD47, an integrin-associated protein (IAP) ubiquitously expressed on hematopoietic and non-hematopoietic cells. CD47 is involved in apoptosis, proliferation, adhesion, and migration, playing a role in immune and angiogenic responses. This antibody neutralizes CD47 in vivo and in vitro, and is studied as a therapeutic treatment for human cancers.
- Reacts with mouse, human, and rat CD47
- Clone MIAP410, Mouse IgG1, κ isotype
- Immunogen is purified human placental CD47
- Formulation: PBS, pH 7.0; contains no stabilizers or preservatives
- Endotoxin: ≤1EU/mg; Purity: ≥95% by SDS-PAGE
- Sterility: 0.2 μm filtration; Purification: Protein G
- Applications include in vivo/in vitro CD47 blockade and immunofluorescence
- Molecular weight: 150 kDa
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