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Bio X Cell InVivoMAb Anti-Mouse CD40L (CD154), MR-1, 25 MG
Supplier: Bio X Cell BE00171R025MG
The MR-1 monoclonal antibody targets mouse CD154 (CD40 ligand), a 39 kDa accessory molecule crucial for T and B lymphocyte costimulation. It inhibits in vitro B lymphocyte activation by blocking CD154 binding, disrupting germinal center formation, and interfering with T cell responses.
- Clone: MR-1
- Reacts with mouse CD154
- Isotype: Armenian hamster IgG
- Immunogen: Activated mouse Th1 clone D1.6
- Reported applications: In vivo/in vitro blocking of CD40/CD40L signaling, Western blot, in vitro Organoids/Organ-on-Chip
- Formulation: PBS, pH 7.0 (no stabilizers or preservatives)
- Endotoxin: ≤1 EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Purification: Protein A
- Molecular Weight: 150 kDa
- Storage: 4°C, do not freeze
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