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Bio X Cell Anti-Mouse CTLA-4 9H10 Hamster IgG, 50 MG
Supplier: Bio X Cell BP0131R050MG
The 9H10 monoclonal antibody targets mouse CTLA-4 (CD152), a 33 kDa cell surface receptor that negatively regulates cell-mediated immune responses. It promotes T cell co-stimulation by blocking CTLA-4 binding to B7 co-receptors, allowing for CD28 binding.
- Suitable for in vivo and in vitro CTLA-4 neutralization and Western blot applications
- Unconjugated and manufactured in an animal-free facility
- Undergoes rigorous quality control, including advanced binding validation and murine pathogen screening
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Endotoxin levels ≤0.5 EU/mg and aggregation <5%
- Purity ≥95% and 0.2 μm filtration for sterility
- Molecular weight of 150 kDa
- Store at 4°C; do not freeze
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