Bio X Cell anti-mouse PD-1, Clone RMP1-14, IgG2a, 100 MG

Supplier:  Bio X Cell BP0146R100MG

The RMP1-14 monoclonal antibody reacts with mouse PD-1 (programmed death-1), also known as CD279. PD-1 signals via binding its two ligands, PD-L1 and PD-L2, inhibiting T-cell activation and playing key roles in peripheral tolerance and prevention of autoimmune disease. This antibody blocks the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1.

• In vivo blocking of PD-1/PD-L signaling
• In vitro organoids/organ-on-chip applications
• Isotype: Rat IgG2a, κ
• Purified by protein G
• Formulation: PBS, pH 7.0; contains no stabilizers or preservatives
• Endotoxin: ≤0.5EU/mg (≤0.0005EU/μg)
• Aggregation: <5%
• Purity: ≥95%
• Sterility: 0.2 μm filtration
• Production: Purified from cell culture supernatant in an animal-free facility
• Molecular weight: 150 kDa

Catalog No. NC1253222