Bio X Cell Monoclonal Antibody, Mouse PD-L1, Clone 10F.9G2, Rat IgG2b

Supplier:  Bio X Cell BP0101R050MG

This monoclonal antibody reacts with mouse PD-L1 (programmed death ligand 1), also known as B7-H1 or CD274. It is a 40 kDa type I transmembrane protein expressed on various immune cells and is important in tumor immune evasion. The antibody blocks the interaction between PD-L1 and PD-1, and between PD-L1 and B7-1 (CD80), which inhibits TCR-mediated T cell proliferation and cytokine production.

• Clone 10F.9G2
• Isotype rat IgG2b, κ
• Immunogen mouse CD274
• Formulated in PBS, pH 6.5, with no stabilizers or preservatives
• Purity greater than 95%
• Sterilized by 0.2 µm filtration
• Molecular weight 150 kDa
• Supports in vivo and in vitro PD-L1 blockade, immunofluorescence, immunohistochemistry (frozen), flow cytometry, western blot, and in vitro organoids/organ-on-chip
• Endotoxin level ≤0.5 EU/mg
• Store at 4°C, do not freeze

Catalog No. NC1327755