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Cayman Chemical IpamorelInacetate 10mg

Supplier: Cayman Chemical 3981310 MG
A growth hormone secretagogue and GHS-R1a agonist; binds to COS-7 cells expressing GHS-R1a (Ki = 63.4 nM); induces IP3 accumulation in BHK cells expressing GHS-R1a (EC50 = 46.9 nM); induces GH release in primary rat pituitary cells (EC50 = 1.3 nM); increases plasma levels of GH in rats and pigs (ED50s = 80 and 2.3 nmol/kg, respectively) but does not increase plasma levels of FSH, LH, prolactin, or TSH in pigs at 420 nmol/kg; increases gastric emptying in a rat model of postoperative ileus induced by laparotomy and intestinal manipulation at 0.014 or 0.14 µmol/kg; increases body weight and longitudinal bone growth in rats from 18-450 UG/animal
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