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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 1 G
SDP

Supplier:  Medchemexpress LLC HY15186A1G

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Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, demonstrating significant selectivity against Akt1, Akt2, and Akt3. It is intended for research use only.

  • Highly selective and ATP-competitive pan-Akt inhibitor
  • IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively
  • Exhibits over 600-fold and over 100-fold selectivity for Akt1 against PKA and p70S6K
  • Effective in xenograft models with Akt activation
  • Achieves tumor growth delay, stasis, or regression in vivo

Catalog No. 50-003-74856


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