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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 100 MG
Supplier: Medchemexpress LLC HY15186A100MG
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor. It is provided as a light yellow to yellow solid and is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor.
- Inhibits Akt1, Akt2, and Akt3 with IC50s of 5, 18, and 8 nM, respectively.
- Demonstrates high selectivity against PKA and p70S6K.
- Efficacious in cell lines and xenograft models with Akt activation.
- Can achieve tumor growth delay, stasis, or regression.
- Enhances tumor growth inhibition in combination therapies.
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