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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 2 MG
SDP

Supplier:  Medchemexpress LLC HY15186A2MG

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Ipatasertib dihydrochloride is a highly selective, ATP-competitive pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50s of 5, 18, and 8 nM, respectively. This compound demonstrates significant selectivity for Akt1 over PKA (more than 600-fold) and p70S6K (over 100-fold). In broader kinase profiling, it inhibits only PRKG1α, PRKG1β, and p70S6K by more than 70% at 1 μM concentration.

  • Highly selective, ATP-competitive pan-Akt inhibitor
  • Inhibits Akt1, Akt2, and Akt3 with high potency
  • Demonstrates significant selectivity for Akt1 over PKA and p70S6K
  • Inhibits PRKG1α, PRKG1β, and p70S6K at 1 μM
  • Intended for research use only

Catalog No. 50-003-72141


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