Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000372141

Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 2 MG
SDP

Catalog No. 5000372141
Encompass_Preferred

Ipatasertib dihydrochloride is a highly selective, ATP-competitive pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50s of 5, 18, and 8 nM, respectively. This compound demonstrates significant selectivity for Akt1 over PKA (more than 600-fold) and p70S6K (over 100-fold). In broader kinase profiling, it inhibits only PRKG1α, PRKG1β, and p70S6K by more than 70% at 1 μM concentration.

  • Highly selective, ATP-competitive pan-Akt inhibitor
  • Inhibits Akt1, Akt2, and Akt3 with high potency
  • Demonstrates significant selectivity for Akt1 over PKA and p70S6K
  • Inhibits PRKG1α, PRKG1β, and p70S6K at 1 μM
  • Intended for research use only

Catalog No. 50-003-72141 Supplier Medchemexpress LLC Supplier No. HY15186A2MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Ipatasertib dihydrochloride is a highly selective, ATP-competitive pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50s of 5, 18, and 8 nM, respectively. This compound demonstrates significant selectivity for Akt1 over PKA (more than 600-fold) and p70S6K (over 100-fold). In broader kinase profiling, it inhibits only PRKG1α, PRKG1β, and p70S6K by more than 70% at 1 μM concentration.

  • Highly selective, ATP-competitive pan-Akt inhibitor
  • Inhibits Akt1, Akt2, and Akt3 with high potency
  • Demonstrates significant selectivity for Akt1 over PKA and p70S6K
  • Inhibits PRKG1α, PRKG1β, and p70S6K at 1 μM
  • Intended for research use only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.