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Medchemexpress LLC Ipratropium bromide hydrate | 66985-17-9 | 99.9% | 500 MG

Supplier: Medchemexpress LLC HYB1332500MG
Ipratropium bromide hydrate is a muscarinic receptor antagonist that relaxes smooth muscle. It can be used in research for COPD (chronic obstructive pulmonary disease) and asthma.
- Muscarinic receptor antagonist
- IC50s of 2.9 nM for M1, 2 nM for M2, and 1.7 nM for M3 receptors
- Exerts toxic effects via disruption of mitochondrial membrane potential
- Increases infarct size in isolated perfused heart ischaemia/reperfusion experiments with a dose-responsive manner
- Inhibits adult rat cardiac myocyte growth after hypoxia treatment
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