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Cayman Chemical IpsapIronhydrochlorIde 10mg

Supplier: Cayman Chemical 2207510 MG
A partial agonist of serotonin 5-HT1A receptors (Ki = 10 nM in hippocampal membranes); reduces 5-HT release in rat ventral hippocampus in vivo; low doses decrease, while high doses increase, extracellular dopamine release in murine nucleus accumbens; extracellular dopamine levels in murine striatum increase following administration at concentrations >0.1 mg/kg; has anxiolytic effects in vivo, inhibiting foot shock-induced aggression and passive avoidance behavior in rats (ED50s = 2.2 and 0.5 mg/kg, respectively)
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