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Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML
Supplier: Medchemexpress LLC HY127105A10MM/1ML
Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. It prevents the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G by exerting a proximal effect in the complement cascade reaction. It can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).
- Effective and orally-active highly selective factor B inhibitor
- IC50 value of 10 nM and KD of 7.9 nM
- Prevents destruction (hemolysis) of red blood cells in PNH
- Prevents damage of renal cells in IgAN and C3G
- Used for the study of complement-mediated diseases
- Particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)
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