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Medchemexpress LLC IRAK4-IN-14 | 2667681-71-0 | 99.0% | 489.55 | 50 MG
SDP

Catalog No. 5000363819
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IRAK4-IN-14 (compound 28) is a potent, selective, and orally active IRAK4 inhibitor with an IC50 of 0.003 μM. It exhibits good PK parameters in rats and mice. IRAK4-IN-14 also demonstrates synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL when combined with Acalabrutinib. It is intended for research use only.

  • Potent, selective, and orally active IRAK4 inhibitor
  • IC50 of 0.003 μM for IRAK4
  • Good PK parameters in rats and mice
  • Synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL when combined with Acalabrutinib
  • Intended for research use only

Catalog No. 50-003-63819 Supplier Medchemexpress LLC Supplier No. HY14611250MG
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IRAK4-IN-14 (compound 28) is a potent, selective, and orally active IRAK4 inhibitor with an IC50 of 0.003 μM. It exhibits good PK parameters in rats and mice. IRAK4-IN-14 also demonstrates synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL when combined with Acalabrutinib. It is intended for research use only.

  • Potent, selective, and orally active IRAK4 inhibitor
  • IC50 of 0.003 μM for IRAK4
  • Good PK parameters in rats and mice
  • Synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL when combined with Acalabrutinib
  • Intended for research use only

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