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Selleck Chemical LLC Tucatinib (Irbinitinib, ONT-380) 5mg 937263-43-9 ARRY-380
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Supplier:  Selleck Chemical LLC S83625MG

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Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-136-6437


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