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Invivogen THP1-Dual™ KO-IRF5 Cells, IRF5 Knockout, Monocytic Cell Line, 2 Cells
Supplier: Invivogen THPDKOIRF5
THP1-Dual™ KO-IRF5 Cells provide a robust platform for studying the role of IRF5 in immune signaling. Engineered from THP1-Dual™ cells with a stable knockout of the IRF5 gene, they enable simultaneous monitoring of IRF and NF-κB pathways via Lucia luciferase and SEAP reporter genes. Functional validation confirms reduced NF-κB responses upon stimulation, making these cells essential for research into IRF5-targeting therapeutics.
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