Irinotecan hydrochloride trihydrate, 99%, Thermo Scientific Chemicals

Description

Topoisomerase I inhibitor

Topoisomerase I inhibitor

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 136572-09-3
• Molecular Formula: C33H39ClN4O6
• Molecular Weight (g/mol): 623.15
• MDL Number: MFCD01862255
• InChI Key: GURKHSYORGJETM-WAQYZQTGSA-N
• Synonym: irinotecan hydrochloride, irinotecan hcl, topotecin, campto, cpt-11, cpt 11, camptothecin 11 hydrochloride, camptothecin 11, unii-06x131e4oe
• PubChem CID: 74990
• ChEBI: CHEBI:5971
• IUPAC Name: hydrogen (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate chloride
• SMILES: [H+].[Cl-].CCC1=C2C=C(OC(=O)N3CCC(CC3)N3CCCCC3)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O

• Melting Point: 256°C
• Color: Yellow
• Quantity: 100 mg
• Merck Index: 14,5091
• Solubility Information: Soluble in DMSO at 100mg/ml; Soluble in water at 25mg/ml with warming
• Formula Weight: 677.19 (623.15 Anhydrous)
• Percent Purity: 99%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Irinotecan hydrochloride trihydrate

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	DW1060750
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only