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Cayman Chemical IsocarboxazId 10mg
Supplier: Cayman Chemical 2362510 MG
An inhibitor of MAO (IC50 = 4.8 μM for rat brain MAO); induces a 4-fold increase in tryptamine action in isolated rat fundal strips at a concentration of 50 nM; potentiates tryptamine toxicity (LD50 = 8 mg/kg following subcutaneous administration of 250 mg/kg tryptamine; inhibits 90% of MAO activity in isolated rat hearts and reduces isoproterenol-induced cardiomegaly in rats; increases levels of dopamine and norepinephrine and reduces levels of the monoamine metabolites DOPAC, HVA, and 5-HIAA in mouse brain
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