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Cayman Chemical Isofagomine (D-tartrate), 957230-65-8, 10 mg
Supplier: Cayman Chemical 1613710
A competitive inhibitor of human lysosomal β-glucosidase (Ki = 0.016-0.025 µM; IC50 = 0.06 µM) that interacts with the catalytic pocket of β-glucosidase, acting as a chemical chaperone that stabilizes and/or promotes the folding of the enzyme; increases lysosomal β-glucosidase activity by 2- to 3-fold in mutant N370S Gaucher fibroblasts
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