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Cayman Chemical Isoflupredon 10mg
Supplier: Cayman Chemical 3537610 MG
A glucocorticoid and mineralocorticoid receptor agonist (EC50s = 0.877 and 0.007 nM, respectively, in transactivation assays); inhibits LPS-induced NO production in RAW 264.7 macrophages (IC50 = 25.5 nM); topical application of an isoflupredone-containing solution inhibits croton oil-induced EAr edema in rats (ED50 = 51.9 nM); increases MAP and decreases the levels of potassium and sodium in the plasma and urine, respectively, in sheep at 0.6 mg/day; reduces tumor levels of uridine incorporation into 18S and 28S rRNA in a P1798 murine lymphoma model at 25 mg/kg
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