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Medchemexpress LLC Isoforskolin | 64657-21-2 | 5 MG
SDP

Catalog No. 5000419936
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Isoforskolin, also known as Coleonol B, is the principal active component derived from C. forskohlii, a plant native to China. This compound is recognized for its potent anti-inflammatory properties. It works by reducing the secretion of lipopolysaccharide (LPS)-induced cytokines, specifically targeting TNF-α, IL-1β, IL-6, and IL-8, in human mononuclear leukocytes. Research indicates its potential as an anti-inflammatory agent for treating conditions such as Lyme arthritis, where it has been shown to downregulate the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA).

  • Acts as an anti-inflammatory agent
  • Reduces LPS-induced cytokine secretion
  • Potential for treating Lyme arthritis
  • Purity of 98.0%
  • Molecular weight of 410.50
  • Appears as a white to off-white solid
  • Soluble in DMSO at 100 mg/mL
  • For research use only

Catalog No. 50-004-19936 Supplier Medchemexpress LLC Supplier No. HYN69275MG
May include imposed supplier surcharges.
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Isoforskolin, also known as Coleonol B, is the principal active component derived from C. forskohlii, a plant native to China. This compound is recognized for its potent anti-inflammatory properties. It works by reducing the secretion of lipopolysaccharide (LPS)-induced cytokines, specifically targeting TNF-α, IL-1β, IL-6, and IL-8, in human mononuclear leukocytes. Research indicates its potential as an anti-inflammatory agent for treating conditions such as Lyme arthritis, where it has been shown to downregulate the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA).

  • Acts as an anti-inflammatory agent
  • Reduces LPS-induced cytokine secretion
  • Potential for treating Lyme arthritis
  • Purity of 98.0%
  • Molecular weight of 410.50
  • Appears as a white to off-white solid
  • Soluble in DMSO at 100 mg/mL
  • For research use only

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