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Cayman Chemical IsopteropodIn 10mg
Supplier: Cayman Chemical 4023710 MG
An oxindole alkaloid with diverse biological activities; induces activation of PXR in a reporter assay using DPX2 cells expressing the human receptor (EC50 = 0.7656 µM); a positive modulator of M1 mAChRs and 5-HT2 receptor (EC50s = 9.92 and 14.5 µM for the rat receptors, respectively); active against S. aureus and B. subtilis (MICs = 408 and 679 µM, respectively); inhibits the proliferation of CCRF CEM C7H2 lymphoblastic leukemia cells at 100 µM
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