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Medchemexpress LLC Isosinensetin | 17290-70-9 | 372.37 | 20 MG
Supplier: Medchemexpress LLC HYN194120MG
Isosinensetin is a flavonoid compound and an inhibitor of HIV-1 protease and PTP1B (IC50: 2.61 μM; Ki: 0.92 μM). It inhibits P-glycoprotein (P-gp) in MDR1-MDCKII cells. Isosinensetin possesses anti-tumor, anti-viral, anti-inflammatory, and antioxidant effects. It is used in research for various diseases including cancer, inflammation, osteoporosis, and diabetes.
- Inhibits HIV-1 protease and PTP1B
- Inhibits P-glycoprotein
- Possesses anti-tumor, anti-viral, anti-inflammatory, and antioxidant effects
- Used in research for cancer, inflammation, osteoporosis, and diabetes
- Inhibits osteoclast formation and bone resorption
- Alleviates estrogen deficiency-induced osteoporosis
- Increases intracellular calcium ion concentration
- Stimulates GLP-1 secretion
- Inhibits erythrocyte hemolysis
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