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Cayman Chemical IsotretInoIn 50mg
SDP

Supplier:  Cayman Chemical 2164850 MG

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A retinoid; increases the doubling time and transcription of RARβ mRNA in various human oral squamous cell carcinoma cells at 1 μM; inhibits proliferation of primary human sebocytes (IC50 = 10 μM); decreases triglyceride, stearyl ester, and free fatty acid synthesis and modulates keratin expression in primary human sebocytes at 0.1 μM; reduces chronic rejection damage and decreases mRNA expression of IFN-γ and IL-10 in allografts in chronic Fisher344➛Lewis transplant mice at 2 mg/kg per day; slows rod and cone recovery and prevents light-induced photoreceptor damage in an albino rat model of photoreceptor degeneration at 40 mg/kg

Catalog No. 50-298-5834


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