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Medchemexpress LLC Isovaleric acid | 503-74-2 | 97.0% | 102.13 | 5 G
SDP

Catalog No. 5000451388
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Isovaleric acid is an orally active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. It can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders.

  • Inhibits osteoclast differentiation by stimulating AMPK phosphorylation.
  • Promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway.
  • Reduces Na+, K+-ATPase activity in synaptic membranes.
  • Has an inhibitory effect on the expression of osteoclast-related genes.
  • Alleviates acetylcholine-induced colonic smooth muscle contraction.
  • Ameliorates ovariectomy-induced osteoporosis in an ovariectomized mouse model.

Catalog No. 50-004-51388 Supplier Medchemexpress LLC Supplier No. HYW0129805G
May include imposed supplier surcharges.
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Isovaleric acid is an orally active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. It can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders.

  • Inhibits osteoclast differentiation by stimulating AMPK phosphorylation.
  • Promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway.
  • Reduces Na+, K+-ATPase activity in synaptic membranes.
  • Has an inhibitory effect on the expression of osteoclast-related genes.
  • Alleviates acetylcholine-induced colonic smooth muscle contraction.
  • Ameliorates ovariectomy-induced osteoporosis in an ovariectomized mouse model.

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