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Isradipine, 98+%

Catalog No. AAJ63920MA
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Description

L-type calcium channel blocker | CAS: 75695-93-1 | C19H21N3O5 | 371.39 g/mol

Isradipine is a L-type calcium channel blocker, Isradipine has anti-atherosclerotic effects in animals and improves endothelium-mediated nitric oxide (NO)-dependent vasodilation in vitro. Additional studies indicate that Isradipine may provide a neuroprotective effect in a rat model of focal ischemia and that Isradipine produces a dose-dependent sparing of dopamine neuronal fibers and cell bodies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Isradipine is a L-type calcium channel blocker, Isradipine has anti-atherosclerotic effects in animals and improves endothelium-mediated nitric oxide (NO)-dependent vasodilation in vitro. Additional studies indicate that Isradipine may provide a neuroprotective effect in a rat model of focal ischemia and that Isradipine produces a dose-dependent sparing of dopamine neuronal fibers and cell bodies.

Solubility
Soluble in DMSO

Notes
Protect from heat. Store away from oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 75695-93-1
Molecular Formula C19H21N3O5
Molecular Weight (g/mol) 371.39
MDL Number MFCD00153820
InChI Key HMJIYCCIJYRONP-UHFFFAOYNA-N
Synonym isradipine, dynacirc, isradipin, lomir, isrodipine, prescal, dynacirc cr, esradin, clivoten, dynacrine
PubChem CID 3784
IUPAC Name 3-methyl 5-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C

Specifications

Color Yellow
Quantity 10 mg
Merck Index 14,5240
Solubility Information Soluble in DMSO
Formula Weight 371.39
Percent Purity ≥98%
Physical Form Crystalline Powder
Chemical Name or Material Isradipine

Safety and Handling

TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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