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Medchemexpress LLC Itacitinib | 1334298-90-6 | 100.0% | 553.51 | 5 MG
Supplier: Medchemexpress LLC 5MGHY16997
Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1, exhibiting significant selectivity over JAK2, JAK3, and TYK2. It is primarily used in the research of myelofibrosis. This product is for research purposes only and has not been fully validated for medical applications.
- Orally active and selective JAK1 inhibitor
- IC50 of 2 nM for human JAK1
- Over 20-fold selectivity for JAK1 over JAK2
- Over 100-fold selectivity over JAK3 and TYK2
- Used in myelofibrosis research
- For research purposes only
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